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Literature summary for 3.4.24.B8 extracted from

  • Nishimura, H.; Kim, E.; Nakanishi, T.; Baba, T.
    Possible function of the ADAM1a/ADAM2 Fertilin complex in the appearance of ADAM3 on the sperm surface (2004), J. Biol. Chem., 279, 34957-34962.
    View publication on PubMed

Application

Application Comment Organism
medicine loss of ADAM1a results in male infertility due to severely impaired ability of sperm to migrate from the uterus into the oviduct through the uterotubul junction Mus musculus

Protein Variants

Protein Variants Comment Organism
additional information ADAM1a-deficient mice, capable of fertilizing cumulus-intact, zona pellucida-intact eggs in vitro Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
Mus musculus 5783
-

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
sperm
-
Mus musculus
-

Synonyms

Synonyms Comment Organism
ADAM1a
-
Mus musculus