Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli XL1-Blue cells | Sus scrofa |
expression in human kidney 293F cells | Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ameloblastin + H2O | Sus scrofa | MMP-20 processes ameloblastin during the secretory stage of amelogenesis, cleaves glycosylated recombinant porcine ameloblastin after Pro2, Gln130, Gln139, Arg170, and Ala222. MMP-20 generates the 23-kDa ameloblastin starting at Tyr223, as well as the 17-kDa (Val1-Arg170) and 15-kDa (Val1-Gln130) ameloblastin cleavage products that concentrate in the sheath space during the secretory stage | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Sus scrofa | P79287 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ameloblastin + H2O | MMP-20 cleaves ameloblastin after Pro2, Gln130, Gln139, Arg170, and Ala222 | Sus scrofa | ameloblastin fragments | fragments of 23 kDa, 17 kDa, and 15 kDa | ? | |
ameloblastin + H2O | MMP-20 processes ameloblastin during the secretory stage of amelogenesis, cleaves glycosylated recombinant porcine ameloblastin after Pro2, Gln130, Gln139, Arg170, and Ala222. MMP-20 generates the 23-kDa ameloblastin starting at Tyr223, as well as the 17-kDa (Val1-Arg170) and 15-kDa (Val1-Gln130) ameloblastin cleavage products that concentrate in the sheath space during the secretory stage | Sus scrofa | ? | - |
? | |
ameloblastin + H2O | cleaves glycosylated recombinant porcine ameloblastin after Pro2, Gln130, Gln139, Arg170, and Ala222. MMP-20 generates the 23-kDa ameloblastin starting at Tyr223, as well as the 17-kDa (Val1-Arg170) and 15-kDa (Val1-Gln130) ameloblastin cleavage products that concentrate in the sheath space during the secretory stage | Sus scrofa | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
enamelysin | - |
Sus scrofa |
MMP-20 | - |
Sus scrofa |