Literature summary for 3.4.24.B5 extracted from

Abraham, R.; Schaefer, J.; Rothe, M.; Bange, J.; Knyazev, P.; Ullrich, A.
Identification of MMP-15 as an anti-apoptotic factor in cancer cells (2005), J. Biol. Chem., 280, 34123-34132.

Search for more literature for 3.4.24.B5

Application

Application	Comment	Organism
medicine	MMP-15 can protect cells of various cancer types from cell death in vitro, connects metastasis and apoptosis resistance by an unknown regulatory mechanism	Homo sapiens

Cloned(Commentary)

Cloned (Comment)	Organism
cloned into pcDNA 3.1/myc-His and subcloned into pLXSN to yield myc-His-tagged MMP-15	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
additional information	knock-down of MMP-15 increases cell death rate	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P51511	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
Calu-6 cell	-	Homo sapiens	-
HeLa-S3 cell	has highest MMP-15 expression of all cell lines	Homo sapiens	-
lung adenocarcinoma cell	overexpression of MMP-15 in human lung adenocarcinoma compared with normal lung	Homo sapiens	-
MCF-7 cell	-	Homo sapiens	-
MEL-JUSO cell	has lowest MMP-15 expression of all cell lines	Homo sapiens	-
PC-3 cell	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
MMP-15	-	Homo sapiens

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Release 2023.1 (January 2023)