Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
colonic cancer cell | - |
Homo sapiens | - |
colorectal cancer cell | - |
Homo sapiens | - |
HCT-116 cell | - |
Homo sapiens | - |
LS-174T cell | - |
Homo sapiens | - |
SW-620 cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
matrix metalloproteinase 13 | - |
Homo sapiens |
MMP13 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | inhibitor of growth 2, ING2, upregulates expression of MMP13, which enhances cancer invasion and metastasis. MMP13 expression is further enhanced by combination of the synergistically acting ING2 and HDAC1 | up |
General Information | Comment | Organism |
---|---|---|
additional information | the ING2-HDAC1-mSin3A complex members regulates expression of MMP13. Upregulation of ING2 is associated with colon cancer and MMP13-dependent cellular invasion | Homo sapiens |