Literature summary for 3.4.24.B4 extracted from

Ziegler, N.; Alonso, A.; Steinberg, T.; Woodnutt, D.; Kohl, A.; Muessig, E.; Schulz, S.; Tomakidi, P.
Mechano-transduction in periodontal ligament cells identifies activated states of MAP-kinases p42/44 and p38-stress kinase as a mechanism for MMP-13 expression (2010), BMC Cell Biol., 11, 10.

Search for more literature for 3.4.24.B4

Cloned(Commentary)

Cloned (Comment)	Organism
MMP-13 expression and promoter activity analysis, overview	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
periodontal ligament	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
MMP-13	-	Homo sapiens

General Information

General Information	Comment	Organism
additional information	Obedience in the expression of MMP-13 as extracellular matrix remodelling executioner from the activation state of mechano-transducing molecules. The transcription factor c-fos is a constituent of the AP1-complex addressing the MMP-13 promotor. Role of activated MAP-kinases pp38 and pp42/44 in strain-induced expression of the active form of MMP-13, activated, phosphorylated p42/44 and p38 are responsible for the expression of MMP-13, overview	Homo sapiens
physiological function	MMP-13 is involved in the mechano-transduction in periodontal ligament cells, that is crucial for physiological and orthodontic tooth movement-associated periodontal remodelling	Homo sapiens

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Release 2023.1 (January 2023)