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BRENDA support

Literature summary for 3.4.24.B14 extracted from

  • Thomas, J.E.; Rylett, C.M.; Carhan, A.; Bland, N.D.; Bingham, R.J.; Shirras, A.D.; Turner, A.J.; Isaac, R.E.
    Drosophila melanogaster NEP2 is a new soluble member of the neprilysin family of endopeptidases with implications for reproduction and renal function (2005), Biochem. J., 386, 357-366.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression in Drosophila melanogaster S2 cells Drosophila melanogaster

Inhibitors

Inhibitors Comment Organism Structure
thiorphan weak inhibition Drosophila melanogaster

Localization

Localization Comment Organism GeneOntology No. Textmining
soluble
-
Drosophila melanogaster
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Drosophila melanogaster NEP2 plays a role in renal function and spermatogenesis ?
-
?

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
malpighian tubule
-
Drosophila melanogaster
-
testis expressed in cyst cells that surround the elongating spermatid bundles in adult testis Drosophila melanogaster
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
locustatachykinin 1 + H2O
-
Drosophila melanogaster ?
-
?
additional information NEP2 plays a role in renal function and spermatogenesis Drosophila melanogaster ?
-
?

Synonyms

Synonyms Comment Organism
NEP2
-
Drosophila melanogaster