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Literature summary for 3.4.24.87 extracted from

  • Clark, C.C.; Mebius, M.M.; de Maat, S.; Tielens, A.G.M.; de Groot, P.G.; Urbanus, R.T.; Fijnheer, R.; Hazenberg, B.P.C.; van Hellemond, J.J.; Maas, C.
    Truncation of ADAMTS13 by plasmin enhances its activity in plasma (2018), Thromb. Haemost., 118, 471-479 .
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
plasmin truncation of the enzyme by plasmin enhances its activity in blood plasma Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens plasmin cleaves and ultimately inactivates the enzyme ?
-
?
von Willebrand factor + H2O Homo sapiens
-
?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q76LX8
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
FRETS-von Willebrand factor 73 + H2O
-
Homo sapiens ?
-
?
additional information plasmin cleaves and ultimately inactivates the enzyme Homo sapiens ?
-
?
von Willebrand factor + H2O
-
Homo sapiens ?
-
?

Subunits

Subunits Comment Organism
? x * 190000, full-length enzyme, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13
-
Homo sapiens
ADAMTS13
-
Homo sapiens