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Literature summary for 3.4.24.87 extracted from

  • Dwyre, D.M.; Dursteler, B.; Nashelsky, M.; Friedman, K.D.; Raife, T.J.
    Value of ADAMTS13 activity and inhibitor in the postmortem diagnosis of thrombotic thrombocytopenic purpura (2009), J. Clin. Apher., 24, 106-110.
    View publication on PubMed
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Application

Application Comment Organism
diagnostics value of ADAMTS13 activity and inhibitor in the postmortem diagnosis of thrombotic thrombocytopenic purpura, overview Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
additional information an endogenous ADAMTS13 inhibitor can cause enzyme deficiency Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
von Willebrand factor + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
von Willebrand factor + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
ADAMTS13
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function ADAMTS13 activity inhibition causes thrombotic thrombocytopenic purpura, TTP. Microthrombi are prominent in the heart, kidneys, pancreas, and adrenal glands Homo sapiens