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Literature summary for 3.4.24.87 extracted from
- Exosite interactions contribute to tension-induced cleavage of von Willebrand factor by the antithrombotic ADAMTS13 metalloprotease (2006), Proc. Natl. Acad. Sci. USA, 103, 19099-19104.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in T-REx 293 cells | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| von Willebrand factor + H2O | Homo sapiens | - |
? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GST-von Willebrand factor 73 + H2O | contains residues Asp1596-Arg1668 from von Willebrand factor domain A2 | Homo sapiens | ? | - |
? | |
| additional information | does not cleave GST-von Willebrand factor 64 which lacks 9 aa residues (E1660APDLVLQR1668) | Homo sapiens | ? | - |
? | |
| von Willebrand factor + H2O | - |
Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ADAMTS13 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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