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Literature summary for 3.4.24.85 extracted from

  • Guan, M.; Su, L.; Yuan, Y.C.; Li, H.; Chow, W.A.
    Nelfinavir and nelfinavir analogs block site-2 protease cleavage to inhibit castration-resistant prostate cancer (2015), Sci. Rep., 5, 9698 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.85

Inhibitors

Inhibitors Comment Organism Structure
(2E)-N-(2-[[3-(3-methyl-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec-8-yl)propyl]sulfanyl]phenyl)-3-phenylprop-2-enamide
-
 Homo sapiens
(2E)-N-(2-[[3-(3-methyl-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec-8-yl)propyl]sulfanyl]phenyl)-3-phenylprop-2-enamide
-
 Methanocaldococcus jannaschii
1,10-phenanthroline
-
 Homo sapiens
1,10-phenanthroline
-
 Methanocaldococcus jannaschii
1-[(benzoylamino)methyl]-1-[3-(benzylsulfanyl)-1-methoxy-1-oxopropan-2-yl]-4-[(benzylsulfanyl)methyl]-2,5-dioxoimidazolidin-1-ium
-
 Homo sapiens
1-[(benzoylamino)methyl]-1-[3-(benzylsulfanyl)-1-methoxy-1-oxopropan-2-yl]-4-[(benzylsulfanyl)methyl]-2,5-dioxoimidazolidin-1-ium
-
 Methanocaldococcus jannaschii
3-(butan-2-yl)-8-[3-[(4-fluorophenyl)sulfanyl]propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
-
 Homo sapiens
3-(butan-2-yl)-8-[3-[(4-fluorophenyl)sulfanyl]propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
-
 Methanocaldococcus jannaschii
7,8-dimethoxy-1,2,3,11a-tetrahydro-5H,11H-pyrrolo[2,1-c][1,4]benzothiazepine-5,11-dione
-
 Homo sapiens
7,8-dimethoxy-1,2,3,11a-tetrahydro-5H,11H-pyrrolo[2,1-c][1,4]benzothiazepine-5,11-dione
-
 Methanocaldococcus jannaschii
methyl 4-[[4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-oxobutyl]sulfanyl]benzoate
-
 Homo sapiens
methyl 4-[[4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-oxobutyl]sulfanyl]benzoate
-
 Methanocaldococcus jannaschii
nelfinavir nelfinavir is a more potent inhibitor of CED-9 protein cleavage than 1,10-phenanthroline Homo sapiens
nelfinavir nelfinavir is a more potent inhibitor of CED-9 protein cleavage than 1,10-phenanthroline Methanocaldococcus jannaschii

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Methanocaldococcus jannaschii Q57837
-
-

Source Tissue

Source Tissue Comment Organism Textmining
DU-145 cell
-
 Homo sapiens
-
PC-3 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATF6 protein + H2O
-
 Homo sapiens ?
-
 ?
ATF6 protein + H2O
-
 Methanocaldococcus jannaschii ?
-
 ?
CED-9 protein + H2O
-
 Homo sapiens ?
-
 ?
CED-9 protein + H2O
-
 Methanocaldococcus jannaschii ?
-
 ?
CREBH + H2O
-
 Homo sapiens ?
-
 ?
CREBH + H2O
-
 Methanocaldococcus jannaschii ?
-
 ?
SREBP-1 + H2O
-
 Homo sapiens ?
-
 ?
SREBP-1 + H2O
-
 Methanocaldococcus jannaschii ?
-
 ?

Synonyms

Synonyms Comment Organism
S2P
-
 Homo sapiens
S2P
-
 Methanocaldococcus jannaschii
site-2 protease
-
 Homo sapiens
site-2 protease
-
 Methanocaldococcus jannaschii