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Literature summary for 3.4.24.85 extracted from

  • Yu, Z.; Luo, X.; Wang, C.; Ye, J.; Liu, S.; Xie, L.; Wang, F.; Bao, J.
    Baicalin promoted site-2 protease and not site-1 protease in endoplasmic reticulum stress-induced apoptosis of human hepatocellular carcinoma cells (2016), FEBS Open Bio, 6, 1093-1101 .
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATF6 protein + H2O Homo sapiens
-
?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Hep-G2 cell
-
Homo sapiens
-
hepatocellular carcinoma cell
-
Homo sapiens
-
SMMC-7721 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATF6 protein + H2O
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
S2P
-
Homo sapiens
site-2 protease
-
Homo sapiens

General Information

General Information Comment Organism
physiological function the enzyme is the molecular target for baicalin in inducing endoplasmic reticulum stress-mediated hepatocellular carcinoma cell apoptosis Homo sapiens