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Literature summary for 3.4.24.82 extracted from
- Release of hyaluronan and hyaladherins (aggrecan G1 domain and link proteins) from articular cartilage exposed to ADAMTS-4 (aggrecanase 1) or ADAMTS-5 (aggrecanase 2) (2004), Arthritis Rheum., 50, 2839-2848.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Chinese hamster ovary/A2 cell line | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| anion exchange chromatography and cation exchange chromatography | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| articular cartilage | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| aggrecan + H2O | - |
Homo sapiens | fragments of aggrecan | - |
? |  |
| cartilage disc extract supernantant + H2O | - |
Homo sapiens | hyaluron + hyaladherins | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ADAMTS-4 | - |
Homo sapiens |
| aggrecanase 1 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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