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Literature summary for 3.4.24.82 extracted from

  • Gao, G.; Westling, J.; Thompson, V.P.; Howell, T.D.; Gottschall, P.E.; Sandy, J.D.
    Activation of the proteolytic activity of ADAMTS4 (aggrecanase-1) by C-terminal truncation (2002), J. Biol. Chem., 277, 11034-11041.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression of ADAMTS-4 in human chondrosarcoma JJ012 cells Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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ADAMTS stands for: a disintegrin and metalloproteinase with thrombospondin motifs
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Homo sapiens O75173
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Sus scrofa
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Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification in vivo production of proteolytically active ADAMTS-4 requires removal of the prodomain by a furin-like activity and MMP-mediated removal of a portion of the C-terminal spacer domain Homo sapiens