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Literature summary for 3.4.24.82 extracted from
- Sites of aggrecan cleavage by recombinant human aggrecanase-1 (ADAMTS-4) (2000), J. Biol. Chem., 275, 18566-18573.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression of cDNA in Drosophila S2 cells | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Homo sapiens | O75173 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| recombinant ADAMTS-4 | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| aggrecan + H2O | - |
Bos taurus | fragments of aggrecan | - |
? |  |
| aggrecan + H2O | preferred cleavage sites of aggrecanase-1 in descending order: E1667-G1668, E1771-A1772, E1871-L1872, E1480-G1481 and E373-A374 | Homo sapiens | fragments of aggrecan | - |
? | |
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