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Literature summary for 3.4.24.81 extracted from

  • Hogl, S.; Kuhn, P.H.; Colombo, A.; Lichtenthaler, S.F.
    Determination of the proteolytic cleavage sites of the amyloid precursor-like protein 2 by the proteases ADAM10, BACE1 and gamma-secretase (2011), PLoS ONE, 6, e21337.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.81

Inhibitors

Inhibitors Comment Organism Structure
TAPI-1
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293 cell
-
 Homo sapiens
-
SH-SY5Y cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
amyloid precursor-like protein 2 + H2O ADAM10 cleaves after Arg670 Homo sapiens soluble amyloid precursor-like protein 2 ectodomain + amyloid precursor-like protein 2 C-terminal fragments
-
 ?

Synonyms

Synonyms Comment Organism
ADAM10
-
 Homo sapiens