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Literature summary for 3.4.24.81 extracted from

  • Endres, K.; Mitteregger, G.; Kojro, E.; Kretzschmar, H.; Fahrenholz, F.
    Influence of ADAM10 on prion protein processing and scrapie infectiosity in vivo (2009), Neurobiol. Dis., 36, 233-241.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Mus musculus
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General Information

General Information Comment Organism
physiological function ADAM10 has no direct influence on PrPc proteolytic processing in vivo. Overexpression of active ADAM10 in transgenic mice leads to a reduced amount of PrP mRNA Mus musculus