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Literature summary for 3.4.24.81 extracted from
- Platelet-activating factor receptor and ADAM10 mediate responses to Staphylococcus aureus in epithelial cells (2002), Nat. Med., 8, 41-46.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | ADAM10 participates in the response to infection by Staphylococcus aureus | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| epithelial growth factor receptor | Homo sapiens | activation of the receptor leads to cleavage of transmembrane heparin-binding site by ADAM10 in response to infection by Staphylococcus aureus | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
cell line | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| epithelial cell | HM3 cell line | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| epithelial growth factor receptor | activation of the receptor leads to cleavage of transmembrane heparin-binding site by ADAM10 in response to infection by Staphylococcus aureus | Homo sapiens | ? | - |
? | |
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