Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of MMP14 null B6 mice | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
podosome | of immature dendritic cells. Podosomes are spot-like actin-rich structures formed at the ventral surface of monocytic and haematopoietic cells | Mus musculus | 2102 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
B6 mice | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
dendritic cell | - |
Mus musculus | - |
hematopoietic cell | - |
Mus musculus | - |
monocyte | - |
Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
MMP-14 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | podosomes mediate migration of dendritic cells through tissues by means of myosin-II-dependent protrusion coupled to MMP-14-dependent degradation and endocytosis. Degradation, protrusion and endocytosis in this system are dependent on the matrix metalloproteinase MMP-14 | Mus musculus |