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Literature summary for 3.4.24.80 extracted from

  • Barbolina, M.V.; Stack, M.S.
    Membrane type 1-matrix metalloproteinase: substrate diversity in pericellular proteolysis (2008), Semin. Cell Dev. Biol., 19, 24-33.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.80

Activating Compound

Activating Compound Comment Organism Structure
pervanadate
-
 Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
N4-hydroxyamino-2-isobutyl-3-(thienylthiomethyl) succinyl]-L-phenylalamine-methylamide
-
 Homo sapiens
reversion-inducing-cysteine-rich protein
-
 Homo sapiens
TIMP-2
-
 Homo sapiens
TIMP-3
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Homo sapiens 16020
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-375 cell
-
 Homo sapiens
-
endothelial cell
-
 Homo sapiens
-
MiaPaCa-2 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha subunit of low density lipoprotein receptor-related protein + H2O
-
 Homo sapiens ?
-
 ?
betaglycan + H2O
-
 Homo sapiens ?
-
 ?
CD44 + H2O
-
 Homo sapiens ?
-
 ?
E-cadherin + H2O
-
 Homo sapiens ?
-
 ?
extracellular matrix metalloproteinase inducer + H2O
-
 Homo sapiens ?
-
 ?
Fibronectin + H2O
-
 Homo sapiens ?
-
 ?
mannose-binding lectin + H2O
-
 Homo sapiens ?
-
 ?
additional information pro-alpha2 integrin subunit is not a substrate Homo sapiens ?
-
 ?
MUC-1 + H2O
-
 Homo sapiens ?
-
 ?
N-cadherin + H2O
-
 Homo sapiens ?
-
 ?
pro-alpha5 integrin subunit + H2O
-
 Homo sapiens ?
-
 ?
pro-alpha5beta3 integrin subunit + H2O
-
 Homo sapiens ?
-
 ?
pro-tissue necrosis factor alpha + H2O
-
 Homo sapiens ?
-
 ?
pro-transforming growth factor beta + H2O
-
 Homo sapiens ?
-
 ?
proMMP-13 + H2O activation Homo sapiens ?
-
 ?
proMMP-2 + H2O activation Homo sapiens ?
-
 ?
proMMP-8 + H2O activation Homo sapiens ?
-
 ?
receptor-activator of NF-kB ligand + H2O
-
 Homo sapiens ?
-
 ?
syndecan-1 core protein + H2O
-
 Homo sapiens ?
-
 ?
tissue transglutaminase + H2O
-
 Homo sapiens ?
-
 ?
transglutaminase + H2O
-
 Homo sapiens ?
-
 ?
Type I collagen + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
membrane type 1-matrix metalloproteinase
-
 Homo sapiens
MT1-MMP
-
 Homo sapiens