Any feedback?
Literature summary for 3.4.24.80 extracted from
- A critical role for the membrane-type 1 matrix metalloproteinase in collagen phagocytosis (2006), Mol. Biol. Cell, 17, 4812-4826.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| E-64 | 0.01 mM | Homo sapiens |  |
| GM6001 | 0.025 mM | Homo sapiens | |
| MT1-MMP siRNA | collagen degrading activity is completely lost when MT1-MMP expressing cells are transfected with 100 nM MT1-MMP siRNA | Homo sapiens | |
| TIMP-2 | - |
Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Homo sapiens | 16020 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 60000 | - |
SDS-PAGE | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| fibroblast | - |
Homo sapiens | - |
| HGF cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Type I collagen + H2O | - |
Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| membrane-type 1 matrix metalloproteinase | - |
Homo sapiens |
| MMP-14 | - |
Homo sapiens |
| MT1-MMP | - |
Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
