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Literature summary for 3.4.24.80 extracted from
- MT1-MMP controls tumor-induced angiogenesis through the release of semaphorin 4D (2007), J. Biol. Chem., 282, 6899-6905.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in lentivirus | Mus musculus |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| E240A | catalytically inactive | Mus musculus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | insensitive to TIMP-1 | Mus musculus | |
| TIMP-2 | 0.0001 mM | Mus musculus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Mus musculus | 16020 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| epithelial cell line | - |
Mus musculus | - |
| neck squamous cell carcinoma cell line | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| membrane-bound Semaphorin 4D + H2O | - |
Mus musculus | soluble Semaphorin 4D + ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| membrane type 1-matrix metalloproteinase | - |
Mus musculus |
| MMP14 | - |
Mus musculus |
| MT1-MMP | - |
Mus musculus |
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Release 2023.1 (January 2023)
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