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Literature summary for 3.4.24.80 extracted from

  • Itoh, Y.
    MT1-MMP: a key regulator of cell migration in tissue (2006), IUBMB Life, 58, 589-596.
    View publication on PubMed
Search for more literature for 3.4.24.80

Inhibitors

Inhibitors Comment Organism Structure
additional information not inhibited by TIMP-1 Homo sapiens
reversion-inducing cysteine rich protein
-
 Homo sapiens
testican 1
-
 Homo sapiens
testican 3
-
 Homo sapiens
TIMP-2
-
 Homo sapiens
TIMP-3
-
 Homo sapiens
TIMP-4
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane MMP-1 localizes at membrane structures called lamellipodia and invadopodia Homo sapiens 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ dependent Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
epithelial cell
-
 Homo sapiens
-
fibroblast
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
aggrecan + H2O
-
 Homo sapiens ?
-
 ?
CD44 + H2O
-
 Homo sapiens ?
-
 ?
Fibrin + H2O
-
 Homo sapiens ?
-
 ?
Fibronectin + H2O
-
 Homo sapiens ?
-
 ?
Laminin-1 + H2O
-
 Homo sapiens ?
-
 ?
laminin-5 beta3 chain + H2O
-
 Homo sapiens ?
-
 ?
proMMP-13 + H2O activation Homo sapiens ?
-
 ?
proMMP-2 + H2O activation Homo sapiens ?
-
 ?
proMMP-8 + H2O activation Homo sapiens ?
-
 ?
syndecan-1 + H2O
-
 Homo sapiens ?
-
 ?
Type I collagen + H2O
-
 Homo sapiens ?
-
 ?
type II collagen + H2O
-
 Homo sapiens ?
-
 ?
type III collagen + H2O
-
 Homo sapiens ?
-
 ?
Vitronectin + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
membrane type 1 matrix metalloproteinase
-
 Homo sapiens
MMP14
-
 Homo sapiens
MT1-MMP
-
 Homo sapiens