Cloned (Comment) | Organism |
---|---|
expressed in COS-7 cells | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
alpha1-PIMT1 | alpha1-proteinase inhibitor-based inhibitor by incorporating the MT1-MMP propeptide sequence into the alpha1-PI reactive-site loop, inhibits proMT1-MMP activation | Homo sapiens | |
alpha1-PIPDX | alpha1-proteinase inhibitor-based inhibitor with furin consensus cleavage sequence inserted into the reactive-site loop, inhibits proMT1-MMP activation | Homo sapiens | |
sialidase A | - |
Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
66000 | - |
pro-enzyme, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
proMMP-2 + H2O | activation | Homo sapiens | MMP-2 + ? | - |
? | |
Type I collagen + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
membrane-type 1 matrix metalloproteinase | - |
Homo sapiens |
MMP14 | - |
Homo sapiens |
MT1-MMP | - |
Homo sapiens |