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Literature summary for 3.4.24.80 extracted from

  • Deschamps, A.M.; Zavadzkas, J.; Murphy, R.L.; Koval, C.N.; McLean, J.E.; Jeffords, L.; Saunders, S.M.; Sheats, N.J.; Stroud, R.E.; Spinale, F.G.
    Interruption of endothelin signaling modifies membrane type 1 matrix metalloproteinase activity during ischemia and reperfusion (2008), Am. J. Physiol. Heart Circ. Physiol., 294, H875-H883.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.80

Activating Compound

Activating Compound Comment Organism Structure
endothelin
-
 Sus scrofa
Protein kinase C
-
 Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Sus scrofa 16020
-
membrane the enzyme is a membrane type 1 protein Sus scrofa 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Sus scrofa MT1-MMP is increased in myocardial ischemia and reperfusion, and contributes to myocardial dysfunction, upstream induction mechanism by release of endothelin and protein kinase C activation, microdialysis analysis, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
endothelial cell
-
 Sus scrofa
-
heart MT1-MMP is increased in myocardial ischemia and reperfusion, myocardial, interstitial enzyme, microdialysis analysis, overview Sus scrofa
-
myocardium
-
 Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(7-methoxycoumarin-4-yl)-acetyl-Pro-Leu-Ala-Cys(p-OmeBz)-Trp-Ala-Arg(Dpa)-NH2 + H2O
-
 Sus scrofa ?
-
 ?
additional information MT1-MMP is increased in myocardial ischemia and reperfusion, and contributes to myocardial dysfunction, upstream induction mechanism by release of endothelin and protein kinase C activation, microdialysis analysis, overview Sus scrofa ?
-
 ?

Synonyms

Synonyms Comment Organism
interstitial MT1-MMP
-
 Sus scrofa
membrane type 1 matrix metalloproteinase
-
 Sus scrofa
MT1-MMP
-
 Sus scrofa