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Literature summary for 3.4.24.80 extracted from
- Spatial and temporal expression profiles suggest the involvement of gelatinase A and membrane type 1 matrix metalloproteinase in amphibian metamorphosis (2006), Cell Tissue Res., 324, 105-116.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| thyroid hormone | indirectly regulates expression of the gene | Xenopus laevis |
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | MT1-MMP and MMP gelatinase A function together in the extracellular matrix degradation or remodeling associated with metamorphosis, MT1-MMP has additional MMP gelatinase A independent roles in the development of adult longitudinal muscle in the intestine | Xenopus laevis |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| cloned intop pCR-Blunt II TOPO vector | Xenopus laevis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Xenopus laevis | Q5USC3 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| intestine | MT1-MMP is upregulated during metamorphosis and coexpressed with MMP gelatinase A in connective tissue during both natural and thyroid-hormone-induced metamorphosis, MT1-MMP is also expressed in the longitudinal muscle cells of the metamorphosing intestine | Xenopus laevis | - |
| tail | MT1-MMP is upregulated during metamorphosis | Xenopus laevis | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| membrane type 1 matrix metalloproteinase | - |
Xenopus laevis |
| membrane type MMP-1 | - |
Xenopus laevis |
| MT1-MMP | - |
Xenopus laevis |
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