Cloned (Comment) | Organism |
---|---|
two truncated forms: CAT domain and CAT/PEX domain | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
AGN3340 | - |
Homo sapiens | |
GM6001 | hydroxamate inhibitor, 0.001 mM, converts protease into a cell surface receptor for receptor of complement component 1q and promotes co-precipitation of the enzyme with the soluble receptor protein | Homo sapiens | |
additional information | no inhibitor: TIMP-1 | Homo sapiens | |
TIMP-2 | tissue inhibitor of metalloproteinases | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P50281 | - |
- |
Purification (Comment) | Organism |
---|---|
catalytic domain | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
alpha1-antitrypsin + H2O | - |
Homo sapiens | ? | - |
? | |
progelatinase A + H2O | syn: pro-matrix metalloproteinase 2, leads to activation of progelatinase A | Homo sapiens | ? | - |
? | |
receptor of complement component 1q + H2O | cleaves at Gly79-Gln80, cleavage with CAT/PEX domain leads to fragments with the following MW: 17 kDa, 12 kDa and 11 kDa | Homo sapiens | ? | - |
? |