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Literature summary for 3.4.24.79 extracted from

  • Cirillo, P.; Conte, S.; Pellegrino, G.; Ziviello, F.; Barra, G.; De Palma, R.; Leonardi, A.; Trimarco, B.
    Pregnancy-associated plasma protein-A promotes TF procoagulant activity in human endothelial cells by Akt-NF-kappaB axis (2016), J. Thromb. Thrombolysis, 42, 225-232 .
    View publication on PubMed
Search for more literature for 3.4.24.79

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ dependent on Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
insulin-like growth factor binding protein-4 + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q13219
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
 Homo sapiens
-
endothelial cell
-
 Homo sapiens
-
HUVEC cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
insulin-like growth factor binding protein-4 + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
PAPP-A
-
 Homo sapiens
pregnancy-associated plasma protein-A
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens enzyme blood plasma levels are elevated in patients with acute coronary syndrome up

General Information

General Information Comment Organism
physiological function the enzyme induces tissue factor expression in epithelial cells through the activation of Akt/nuclear factor-kappaB axis Homo sapiens