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Literature summary for 3.4.24.79 extracted from

  • Kloverpris, S.; Mikkelsen, J.H.; Pedersen, J.H.; Jepsen, M.R.; Laursen, L.S.; Petersen, S.V.; Oxvig, C.
    Stanniocalcin-1 potently inhibits the proteolytic activity of the metalloproteinase pregnancy-associated plasma protein-A (2015), J. Biol. Chem., 290, 21915-21924 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.79

Inhibitors

Inhibitors Comment Organism Structure
stanniocalcin-1
-
 Homo sapiens
stanniocalcin-2
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
insulin-like growth factor binding protein-2 + H2O Homo sapiens
-
 ?
-
 ?
insulin-like growth factor binding protein-4 + H2O Homo sapiens
-
 ?
-
 ?
insulin-like growth factor binding protein-5 + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q13219
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
insulin-like growth factor binding protein-2 + H2O
-
 Homo sapiens ?
-
 ?
insulin-like growth factor binding protein-4 + H2O
-
 Homo sapiens ?
-
 ?
insulin-like growth factor binding protein-5 + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
PAPP-A isoform Homo sapiens
PAPP-A2 isoform Homo sapiens
pregnancy-associated plasma protein-A
-
 Homo sapiens

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.000000068
-
 stanniocalcin-1 isoform PAPP-A, at pH 7.5 and 37°C Homo sapiens