Literature summary for 3.4.24.79 extracted from

Amor, D.J.; Xu, J.X.; Halliday, J.L.; Francis, I.; Healy, D.L.; Breheny, S.; Baker, H.W.; Jaques, A.M.
Pregnancies conceived using assisted reproductive technologies (ART) have low levels of pregnancy-associated plasma protein-A (PAPP-A) leading to a high rate of false-positive results in first trimester screening for Down syndrome (2009), Hum. Reprod., 24, 1330-1338.

Search for more literature for 3.4.24.79

Application

Application	Comment	Organism
medicine	a detailed analysis is performed of first trimester screening results in singleton pregnancies conceived using assisted reproductive technologies and non-assisted reproductive technologies pregnancies. A record linkage study compared outcomes in 1739 assisted reproductive technologies-conceived and 50.253 naturally conceived pregnancies. Assisted reproductive technologies pregnancies have reduced first trimester screening PAPP-A levels leading to an increased likelihood of receiving a false-positive result and having a CVS/amniocentesis. Lower PAPP-A may reflect impairment of early implantation with some forms of assisted reproductive technologies	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Synonyms

Synonyms	Comment	Organism
PAPP-A	-	Homo sapiens
pregnancy-associated plasma protein-A	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)