Application | Comment | Organism |
---|---|---|
diagnostics | increased pregnancy-associated plasma protein-A is a marker for peripheral atherosclerosis, Linz Peripheral Arterial Disease Study | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Homo sapiens | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | PAPP-A is a zinc-binding metalloproteinase | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | PAPP-A is involved in acute coronary syndrome, and is associated with atherosclerotic peripheral arterial disease, PAD, i.e. chronic limb ischemia, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
healthy individuals and patients with symptomatic atherosclerotic, i.e. chronic limb ischemia | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
serum | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
serum PAPP-A concentrations are measured with an enzymatically amplified 2-step sandwich-type immunoassay | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | PAPP-A is involved in acute coronary syndrome, and is associated with atherosclerotic peripheral arterial disease, PAD, i.e. chronic limb ischemia, overview | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PAPP-A | - |
Homo sapiens |
pregnancy-associated plasma protein-A | - |
Homo sapiens |