Literature summary for 3.4.24.79 extracted from

Miyakoshi, N.; Qin, X.; Kasukawa, Y.; Richman, C.; Srivastava, A.K.; Baylink, D.J.; Mohan, S.
Systemic administration of insulin-like growth factor (IGF)-binding protein-4 (IGFBP-4) increases bone formation parameters in mice by increasing IGF bioavailability via an IGFBP-4 protease-dependent mechanism (2001), Endocrinology, 142, 2641-2648.

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Application

Application	Comment	Organism
medicine	administation of insulin-like growth factor binding protein (IGFBP)-4 causes significant increase in bone formation parameters, possibly through increased IGF bioavailability via proteolysis of insulin-like growth factor binding protein (IGFBP)-4	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
insulin-like growth factor binding protein-4 + H2O	-	Mus musculus	?	-	?

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Release 2023.1 (January 2023)