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Literature summary for 3.4.24.75 extracted from

  • Narasimhaswamy, N.; Bairy, I.; Shenoy, G.; Bairy, L.
    In vitro activity of recombinant lysostaphin in combination with linezolid, vancomycin and oxacillin against methicillin-resistant Staphylococcus aureus (2017), Iran. J. Microbiol., 9, 208-212 .
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine the enzyme can be used in life-threatening infections, such as endocarditis to increase the early in vivo activity of the antibiotics, and to prevent the emergence of linezolid resistant mutants Staphylococcus simulans

Organism

Organism UniProt Comment Textmining
Staphylococcus simulans
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
methicillin-resistant Staphylococcus aureus cells + H2O the enzyme causes rapid lysis of Staphylococcus aureus cells Staphylococcus simulans ?
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