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Literature summary for 3.4.24.75 extracted from
- The phage K lytic enzyme LysK and lysostaphin act synergistically to kill MRSA (2008), FEMS Microbiol. Lett., 287, 185-191.
General Stability
| General Stability | Organism |
|---|---|
| relatively unaffected by salt concentrations between 200 and 500 mM, LysK has a higher specific activity than lysostaphin at NaCl concentrations higher than 150 mM (turbidity reduction assay) | Staphylococcus simulans |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 26800 | - |
246 amino acids, mature peptide, recombinant enzyme | Staphylococcus simulans |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Staphylococcus simulans | - |
- |
- |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
lysostaphin inhibits growth of methicillin-resistant Staphylococcus aureus USA300 at a concentration of 0.096 mg/ml. Growth inhibition of the two enzymes lysostaphin and LysK in combination is greater than either enzyme alone | Staphylococcus simulans |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| lysostaphin | - |
Staphylococcus simulans |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6 | - |
highest specific activity (turbidity reduction assay) | Staphylococcus simulans |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 6 | 9 | strong activity (turbidity reduction assay) | Staphylococcus simulans |
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Release 2023.1 (January 2023)
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