Any feedback?
Literature summary for 3.4.24.75 extracted from
- Lysostaphin (2004), Handbook of Proteolytic Enzymes (Barrett, J. ; Rawlings, N. D. ; Woessner, J. F. , eds. ) Academic Press, 1, 1004-1005.
No PubMed abstract available
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | staphylococcal disease pathogenesis | Staphylococcus simulans |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,10-phenanthroline | - |
Staphylococcus simulans |  |
| EDTA | - |
Staphylococcus simulans | |
| additional information | binding of elastin to lysostaphin is not affected by exogenously added zinc, suggesting that zinc interferes directly with the catalytic activity of the enzyme | Staphylococcus simulans | |
| Zn2+ | - |
Staphylococcus simulans | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 27000 | - |
mature enzyme | Staphylococcus simulans |
| 42000 | - |
preproenzyme | Staphylococcus simulans |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Staphylococcus simulans | - |
biovar Staphylococcus simulans staphylolyticus | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| ammonium sulfate precipitation and ion exchange chromatography | Staphylococcus simulans |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Peptidoglycan + H2O | - |
Staphylococcus simulans | Fragments of peptidoglycan | - |
? | |
| soluble elastin + H2O | - |
Staphylococcus simulans | ? | - |
? | |
pI Value
| Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|
| Staphylococcus simulans | mature enzyme | - |
9.7 |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
