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Literature summary for 3.4.24.73 extracted from

  • Baldo, C.; Tanjoni, I.; Leon, I.R.; Batista, I.F.; Della-Casa, M.S.; Clissa, P.B.; Weinlich, R.; Lopes-Ferreira, M.; Lebrun, I.; Amarante-Mendes, G.P.; Rodrigues, V.M.; Perales, J.; Valente, R.H.; Moura-da-Silva, A.M.
    BnP1, a novel P-I metalloproteinase from Bothrops neuwiedi venom: biological effects benchmarking relatively to jararhagin, a P-III SVMP (2008), Toxicon, 51, 54-65.
    View publication on PubMed
Search for more literature for 3.4.24.73

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Bothrops jararaca
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+
-
 Bothrops jararaca
additional information the enzyme is a P-III snake venom metalloproteinase Bothrops jararaca

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Fibrinogen + H2O Bothrops jararaca
-
 ?
-
 ?
additional information Bothrops jararaca the enzyme is a P-III snake venom metalloproteinase and a potent hemorrhagin, it induces strong pro-inflammatory response increasing the number of rolling leukocytes within capillary vessels, jararhagin induces apoptosis and release of angiostatin-like peptides in human endothelial cells, overview ?
-
 ?
von Willebrand factor + H2O Bothrops jararaca
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Bothrops jararaca
-
-
-

Purification (Commentary)

Purification (Comment) Organism
native enzyme from venom Bothrops jararaca

Source Tissue

Source Tissue Comment Organism Textmining
venom
-
 Bothrops jararaca
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Fibrinogen + H2O
-
 Bothrops jararaca ?
-
 ?
Fibrinogen + H2O bovine substrate Bothrops jararaca ?
-
 ?
additional information the enzyme is a P-III snake venom metalloproteinase and a potent hemorrhagin, it induces strong pro-inflammatory response increasing the number of rolling leukocytes within capillary vessels, jararhagin induces apoptosis and release of angiostatin-like peptides in human endothelial cells, overview Bothrops jararaca ?
-
 ?
von Willebrand factor + H2O
-
 Bothrops jararaca ?
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Bothrops jararaca

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.3
-
 assay at Bothrops jararaca