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Literature summary for 3.4.24.72 extracted from
- Purification and antithrombotic activity of wulfase, a fibrinolytic enzyme from the fruit bodies of the edible and medicinal mushroom Sparassis crispa Wulf. ex. Fr (2016), Appl. Biochem. Microbiol., 52, 608-614 .
No PubMed abstract available
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | the enzyme is useful for reducing or preventing thrombotic challenge | Sparassis crispa |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sparassis crispa | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| DEAE Sepharose column chromatography and Q Sepharose column chromatography | Sparassis crispa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| fruit body | - |
Sparassis crispa | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| fibrin clot + H2O | the enzyme induces inhibition of fibrin clot formation in a concentration-dependent manner | Sparassis crispa | ? | - |
? |  |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 90000, SDS-PAGE | Sparassis crispa |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| fibrinolytic enzyme | - |
Sparassis crispa |
| wulfase | - |
Sparassis crispa |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | the enzyme can inhibit activities of factor Xa and thrombin | Sparassis crispa |
| physiological function | the enzyme inhibits fibrin polymer formation (anticoagulant effect) | Sparassis crispa |
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