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Literature summary for 3.4.24.72 extracted from

  • Retzios, A.D.; Markland, F.S.
    A direct-acting fibrinolytic enzyme from the venom of Agkistrodon contortrix contortrix: effects on various components of the human blood coagulation and fibrinolysis systems (1988), Thromb. Res., 52, 541-552.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Agkistrodon contortrix contortrix
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
venom
-
Agkistrodon contortrix contortrix
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Fibrin Aalpha-chain + H2O human, cleavage at Lys413-Lys414, the Bbeta-chain is cleaved more slowly and the gamma-chain is minimally affected Agkistrodon contortrix contortrix ?
-
?
Fibrinogen Aalpha-chain + H2O human Agkistrodon contortrix contortrix ?
-
?
Fibrinogen Aalpha-chain + H2O cleavage at Lys413-Leu414 (initial cleavage) Agkistrodon contortrix contortrix ?
-
?
Fibrinogen Aalpha-chain + H2O the Bbeta-chain is cleaved more slowly and the gamma-chain is minimally affected Agkistrodon contortrix contortrix ?
-
?
additional information does not activate protein C Agkistrodon contortrix contortrix ?
-
?
additional information does not activate plasminogen Agkistrodon contortrix contortrix ?
-
?