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Literature summary for 3.4.24.71 extracted from

  • Heyman, S.N.; Abassi, Z.; Rosenberger, C.; Yaseen, H.; Skarjinski, G.; Shina, A.; Mathia, S.; Krits, N.; Khamaisi, M.
    Cyclosporine A induces endothelin-converting enzyme-1 Studies invivo and invitro (2018), Acta Physiol. (Oxf.), 223, e13033 .
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
big endothelin + H2O Rattus norvegicus
-
 endothelin-1 + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus P42893
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
big endothelin + H2O
-
 Rattus norvegicus endothelin-1 + ?
-
 ?

Synonyms

Synonyms Comment Organism
ECE-1
-
 Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus cyclosporine A intensifies renal enzyme expression. The enzyme is upregulated by hypoxia via hypoxia-inducible factor up