Cloned (Comment) | Organism |
---|---|
expressed in NCM-460 cells | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
SM-19712 | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endosome | - |
Homo sapiens | 5768 | - |
membrane | transmembrane protein | Homo sapiens | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Substance P + H2O | Homo sapiens | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P42892 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
colonocyte | - |
Homo sapiens | - |
HEK-293 cell | - |
Homo sapiens | - |
NCM-460 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Substance P + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ECE-1 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | the primary function of ECE-1 in substance P-dependent inflammatory signaling is to promote resensitization, which allows the sustained neurokinin 1 receptor signaling from the plasma membrane that drives inflammation | Homo sapiens |