Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | diabetes and radiocontrast media increase medullary, but not cortical endothelin converting enzyme-1 content in the kidney, in vivo, the induction of diabetes or the administration of contrast media rises the enzyme activity 4-5fold, but 15fold when diabetic rats are given contrast media, the in vitro activity is increased 3-4fold, overview | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
preproendothelin-1 + H2O | Rattus norvegicus | - |
endothelin-1 + ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
healthy and streptozotocin-induced diabetic rats | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | medulla and cortex, expression analysis after enzyme induction, overview | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
preproendothelin-1 + H2O | - |
Rattus norvegicus | endothelin-1 + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ECE-1 | - |
Rattus norvegicus |
endothelin-converting enzyme-1 | - |
Rattus norvegicus |