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Literature summary for 3.4.24.71 extracted from
- Phosphorylation of endothelin converting enzyme-1 isoforms: relevance to subcellular localization (2006), Exp. Biol. Med., 231, 713-717.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| Golgi apparatus | isozymes ECE-1a and ECE-1c | Homo sapiens | 5794 | - |
| lysosome | isozyme ECE-1b | Homo sapiens | 5764 | - |
| additional information | maintenance of cells in high glucose at 25 mM promotes relocalization of ECE-1a from the membrane to the intracellular compartment, mechanism, overview, phosphorylation might play an important role in the regulation of intracellular trafficking of ECE-1 subisoforms | Homo sapiens | - |
- |
| nuclear membrane | ECE-1a but not ECE-1b co-localizes with nuclear membrane markers | Homo sapiens | 31965 | - |
| plasma membrane | isozymes ECE-1a and ECE-1c | Homo sapiens | 5886 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| additional information | metalloenzyme | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
4 isozymes ECE-1a-d | - |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| phosphoprotein | the isozymes contain a different number of putative phosphorylation sites for protein kinase C and protein kinase A in the amino-terminal region, stimulation of phosphorylation by phorbol myristate acetate, inhibition by calphostin C, phosphorylation might play an important role in the regulation of intracellular trafficking of ECE-1 subisoforms | Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ECE-1 | - |
Homo sapiens |
| endothelin converting enzyme-1 | - |
Homo sapiens |
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