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Literature summary for 3.4.24.7 extracted from

  • Lian, I.A.; Toft, J.H.; Olsen, G.D.; Langaas, M.; Bjorge, L.; Eide, I.P.; Bordahl, P.E.; Austgulen, R.
    Matrix metalloproteinase 1 in pre-eclampsia and fetal growth restriction: reduced gene expression in decidual tissue and protein expression in extravillous trophoblasts (2010), Placenta, 31, 516-520.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
extravillous trophoblast
-
Homo sapiens
-
fetus
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Homo sapiens
-
additional information MMP-1 is downregulated 4fold during trophoblast differentiation, reduced MMP-1 expression in pre-eclampsia and fetal growth restriction Homo sapiens
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Synonyms

Synonyms Comment Organism
collagenase
-
Homo sapiens
matrix metalloproteinase-1
-
Homo sapiens
MMP-1
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens MMP-1 is downregulated 4fold during trophoblast differentiation, reduced MMP-1 expression in pre-eclampsia and fetal growth restriction down

General Information

General Information Comment Organism
malfunction MMP-1 is downregulated 4fold during trophoblast differentiation, reduced MMP-1 expression in pre-eclampsia and fetal growth restriction Homo sapiens
physiological function throughout the process of invading and remodelling spiral arteries, extracellular matrix must be broken down and matrix metalloproteinases are major participants in this disintegration Homo sapiens