Cloned (Comment) | Organism |
---|---|
quantitative MMP-1 expression analysis in skin fibroblasts | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | dependent on | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
type I procollagen + H2O | Homo sapiens | - |
type I collagen + ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
CCD-986Sk cell | - |
Homo sapiens | - |
fibroblast | - |
Homo sapiens | - |
skin | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
type I procollagen + H2O | - |
Homo sapiens | type I collagen + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
matrix metalloproteinase-1 | - |
Homo sapiens |
MMP-1 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | inhibition of MMP-1 expression by extracts of Kaempferia pandurata, overview | down |
Homo sapiens | MMP-1 expression is induced by UV-B irradiation, the induction is inhibited by extracts of Kaempferia pandurata, as are phosphorylation of MAP kinases ERK, JNK, and p38, overview | up |
General Information | Comment | Organism |
---|---|---|
physiological function | MMP-1 is a zinc-dependent endopeptidase capable of degrading all components of the extracellular matrix | Homo sapiens |