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Literature summary for 3.4.24.7 extracted from

  • Shim, J.S.; Choi, E.J.; Lee, C.W.; Kim, H.S.; Hwang, J.K.
    Matrix metalloproteinase-1 inhibitory activity of Kaempferia pandurata Roxb (2009), J. Med. Food, 12, 601-607.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
quantitative MMP-1 expression analysis in skin fibroblasts Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ dependent on Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
type I procollagen + H2O Homo sapiens
-
type I collagen + ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
CCD-986Sk cell
-
Homo sapiens
-
fibroblast
-
Homo sapiens
-
skin
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
type I procollagen + H2O
-
Homo sapiens type I collagen + ?
-
?

Synonyms

Synonyms Comment Organism
matrix metalloproteinase-1
-
Homo sapiens
MMP-1
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens inhibition of MMP-1 expression by extracts of Kaempferia pandurata, overview down
Homo sapiens MMP-1 expression is induced by UV-B irradiation, the induction is inhibited by extracts of Kaempferia pandurata, as are phosphorylation of MAP kinases ERK, JNK, and p38, overview up

General Information

General Information Comment Organism
physiological function MMP-1 is a zinc-dependent endopeptidase capable of degrading all components of the extracellular matrix Homo sapiens