Inhibitors | Comment | Organism | Structure |
---|---|---|---|
tissue inhibitors of metalloproteinase-1 | i.e. TIMP-1 | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Type I collagen + H2O | Homo sapiens | production of type I collagen by periodontal ligament cells | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
periodontal ligament | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Type I collagen + H2O | - |
Homo sapiens | ? | - |
? | |
Type I collagen + H2O | production of type I collagen by periodontal ligament cells | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
matrix metalloproteinase-1 | - |
Homo sapiens |
MMP-1 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | both the MMP-1 and TIMP-1 mRNA expression level are dramatically downregulated by baicalin | down |
Homo sapiens | phorbol 12-myristate 13-acetate and interleukin-1beta significantly stimulate the production of MMP-1 by periodontal ligament cells at both the transcriptional and the translational level | up |
General Information | Comment | Organism |
---|---|---|
metabolism | effects of baicalin on the total protein amount and collagen I mRNA expression in periodontal ligament cells, and the regulatory effects on MMP-1/TIMP-1 expression, overview | Homo sapiens |