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Literature summary for 3.4.24.7 extracted from

  • Igata, T.; Jinnin, M.; Makino, T.; Moriya, C.; Muchemwa, F.C.; Ishihara, T.; Ihn, H.
    Up-regulated type I collagen expression by the inhibition of Rac1 signaling pathway in human dermal fibroblasts (2010), Biochem. Biophys. Res. Commun., 393, 101-105.
    View publication on PubMed
Search for more literature for 3.4.24.7

Cloned(Commentary)

Cloned (Comment) Organism
quantitative MMP-1 expression analysis in primary dermal fibroblasts Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Type I collagen + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast dermal, primary Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Type I collagen + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
collagenase
-
 Homo sapiens
mmp1
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens Rac1 inhibitor NSC23766 suppresses MMP1 in dermal fibroblasts, and half-lives of type I collagen protein are increased down

General Information

General Information Comment Organism
additional information Rac1 signaling results in accumulation of type I collagen due to decreased collagenase activity, overview Homo sapiens