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Literature summary for 3.4.24.69 extracted from

  • Sun, S.; Tepp, W.; Johnson, E.; Chapman, E.
    Botulinum neurotoxins B and E translocate at different rates and exhibit divergent responses to GT1b and low pH (2012), Biochemistry, 51, 5655-5662.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.69

Inhibitors

Inhibitors Comment Organism Structure
concanamycin A
-
 Clostridium botulinum
toosendanin an enzyme translocation inhibitor that hinders subtype BoNT/B oligomerization Clostridium botulinum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
SNAP-25 + H2O Clostridium botulinum
-
 ?
-
 ?
synaptobrevin + H2O Clostridium botulinum
-
 ?
-
 ?
Syntaxin + H2O Clostridium botulinum
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Clostridium botulinum P10844
-
-
Clostridium botulinum Q00496
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
SNAP-25 + H2O
-
 Clostridium botulinum ?
-
 ?
synaptobrevin + H2O
-
 Clostridium botulinum ?
-
 ?
Syntaxin + H2O
-
 Clostridium botulinum ?
-
 ?

Subunits

Subunits Comment Organism
oligomer oligomerization of BoNT/E is dependent only on GT1b and does not require low pH Clostridium botulinum

Synonyms

Synonyms Comment Organism
BoNT/B serotype Clostridium botulinum
BoNT/E serotype Clostridium botulinum
Botulinum neurotoxin
-
 Clostridium botulinum