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Literature summary for 3.4.24.69 extracted from
- Lab-on-a-chip for botulinum neurotoxin a (BoNT-A) activity analysis (2009), Lab Chip, 9, 3275-3281.
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zn2+ | Zn-dependent proteinase | Clostridium botulinum |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Clostridium botulinum | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| SNAP-25 + H2O | i.e. 25-kDa synaptosome-associated protein, design and construction of a lab-on-a-chip for the in vitro detection of BoNT-A activity using an assay that measures cleavage of the fluorescence-labeled peptide substrate specific for BoNT-A by the toxin light chain, detection by Foerster resonance energy transfer, FRET, fluorescence, method development and evaluation, overview. The peptide substrate is labeled with internally labeled with the FRET pair fluorescein-thiocarbamoyl, FITC, and 4-(dimethyla-minoazo)benzene-4-carboxylic acid, DABCYL, or with FITC only for positive control | Clostridium botulinum | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| BoNT-A | - |
Clostridium botulinum |
| botulinum neurotoxin a | - |
Clostridium botulinum |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Clostridium botulinum |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
assay at | Clostridium botulinum |
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Release 2023.1 (January 2023)
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