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Literature summary for 3.4.24.65 extracted from

  • Boyd, S.; Virolainen, S.; Paerssinen, J.; Skoog, T.; van Hogerlinden, M.; Latonen, L.; Kylloenen, L.; Toftgard, R.; Saarialho-Kere, U.
    MMP-10 (Stromelysin-2) and MMP-21 in human and murine squamous cell cancer (2009), Exp. Dermatol., 18, 1044-1052.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
commercial preparation
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Homo sapiens
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macrophage
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Homo sapiens
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skin
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Homo sapiens
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squamous cell carcinoma cell 16-50 SCCs, in situ detection, overview Homo sapiens
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Synonyms

Synonyms Comment Organism
Matrix metalloproteinase-12
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Homo sapiens
MMP-12
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Homo sapiens

Expression

Organism Comment Expression
Homo sapiens UV radiation is known to induce the expression of MMP-12 in skin up

General Information

General Information Comment Organism
physiological function macrophage-derived MMP-12 may activate angiostatin and function in host response. MMP-12 expression in cancer cells correlates with tumor aggressiveness Homo sapiens