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Literature summary for 3.4.24.64 extracted from

  • Burri, L.; Williams, B.A.; Bursac, D.; Lithgow, T.; Keeling, P.J.
    Microsporidian mitosomes retain elements of the general mitochondrial targeting system (2006), Proc. Natl. Acad. Sci. USA, 103, 15916-15920.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.64

Cloned(Commentary)

Cloned (Comment) Organism
DNA and amino acid sequence determination and analysis, expression in Saccharomyces cerevisiae strain JK9-3da/a Antonospora locustae

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Antonospora locustae 16020
-
mitosome inner membrane, a tiny double-membrane-bounded reduced mitochondrion, the mitosome has no genome and must import all its proteins from the cytosol, scheme of Imp1 and Imp2 in the microsporidian mitosome, overview Antonospora locustae 32047
-
additional information reduced complexity of targeting pathways in microsporidian mitosomes, overview Antonospora locustae
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
mitochondrial glycerol-3-phosphate dehydrogenase + H2O Antonospora locustae
-
 processed mitochondrial glycerol-3-phosphate dehydrogenase + prepeptide
-
 ?
additional information Antonospora locustae mitosomal substrates of the enzyme are processed to mature proteins in Antonospora locustae with a simplified processing complex, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Antonospora locustae
-
 a fungal intracellular microsporidian parasite
-
no activity in Encephalitozoon cuniculi
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
mitochondrial glycerol-3-phosphate dehydrogenase + H2O
-
 Antonospora locustae processed mitochondrial glycerol-3-phosphate dehydrogenase + prepeptide
-
 ?
mitochondrial glycerol-3-phosphate dehydrogenase + H2O arginine residue at the -2 position from the MPP cleavage site, a possible processing site is indicated around residue 40, estimated from deletion experiments Antonospora locustae processed mitochondrial glycerol-3-phosphate dehydrogenase + prepeptide
-
 ?
additional information mitosomal substrates of the enzyme are processed to mature proteins in Antonospora locustae with a simplified processing complex, overview Antonospora locustae ?
-
 ?
additional information no activity with the mitochondrial glycerol-3-phosphate dehydrogenase from Encephalitozoon cuniculi Antonospora locustae ?
-
 ?

Synonyms

Synonyms Comment Organism
Imp1
-
 Antonospora locustae
Imp2
-
 Antonospora locustae
inner membrane peptidase processing enzyme
-
 Antonospora locustae