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Literature summary for 3.4.24.57 extracted from

  • Berger, S.B.; Sadighi Akha, A.A.; Miller, R.A.; Garcia, G.G.
    CD43-independent augmentation of mouse T-cell function by glycoprotein cleaving enzymes (2006), Immunology, 119, 178-186.
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus increases alpha-CD3-induced Ca2+ responses in CD4+ T cells, and enhances cytokine production by CD4+ T cells, of both young and old mice, treatment with OSGE can enhance the expression of early activation markers in both WT and CD43 KO mice, overview ?
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 ?
surface CD43 + H2O Mus musculus OSGE improves T-cell function even in mice lacking CD43, showing that other glycoproteins must contribute to the OSGE effect on function, overview ?
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 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
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 CD43 knockout and CD43 wild type mice, on the C57BL/6 background
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Source Tissue

Source Tissue Comment Organism Textmining
T-lymphocyte CD4+ T cell of both young and old mice Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CD43 + H2O a O-linked glycoprotein on T-cell surface Mus musculus ?
-
 ?
additional information increases alpha-CD3-induced Ca2+ responses in CD4+ T cells, and enhances cytokine production by CD4+ T cells, of both young and old mice, treatment with OSGE can enhance the expression of early activation markers in both WT and CD43 KO mice, overview Mus musculus ?
-
 ?
surface CD43 + H2O OSGE improves T-cell function even in mice lacking CD43, showing that other glycoproteins must contribute to the OSGE effect on function, overview Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
OSGE
-
 Mus musculus